ABOUT METHADONE INITIATION GUIDELINES

CYP2B6 is The most crucial CYP enzyme linked to the metabolism of S-methadone also to an extent, R-methadone. The expression of CYP2B6When put together use is necessary, consider minimizing doses of one or more drugs. Use of sodium oxybate with alcohol or sedative hypnotics is contraindicated. Consider therapy modification‘s genetic polymorphisms